Bivalent Oral Poliomyelitis Vaccine Bio Farma Caution For Usage

THE VACCINE VIAL MONITOR: Inner square lighter than outer circle.
If the expiry date has not been passed, USE the vaccine.
At a later time, inner square still lighter than outer circle.
If the expiry date has not been passed, USE the vaccine.
Discard point: Inner square matches colour of outer circle.
DO NOT use the vaccine.
Beyond the discard point: Inner square darker than outer ring.
DO NOT use the vaccine.
Vaccine Vial Monitors (VVMs) are part of the label on all bOPV supply through Temp Time. The colour dot which appears on the label of the vial is a VVM. This is a time-temperature sensitive dot that provides an indication of the cumulative heat to which the vial has been exposed. It warns the end user when exposure to heat is likely to have degraded the vaccine beyond an acceptable level.
The interpretation of the VVM is simple. Focus on the central square. Its colour will change progressively. As long as the colour of this square is lighter than the colour of the ring, then the vaccine can be used. As soon as the colour of the central square is the same colour as the ring or of a darker colour than the ring, then the vial should be discarded.